SIRT7 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6082
Background:
SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions.
Alternative Name:
NAD dependent deacetylase sirtuin 7, NAD-dependent deacetylase sirtuin-7, Silent mating type information regulation 2 homolog, Silent mating type information regulation 2 S.cerevisiae homolog 7, IR2 L7, SIR2 like protein 7, Sir2 related protein type 7, SIR2, S.CEREVISIAE, HOMOLOG-LIKE 7, SIR2-like protein 7, SIR2L 7, SIR2L7, SIRT 7, SIRT7, SIRT7, Sirtuin 7, Sirtuin type 7, Sirtuin7,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: SIRT7 polyclonal antibody detects endogenous levels of SIRT7 protein.
Immunogen:
Recombinant full length Human SIRT7.
MW: ~ 44 kDa
Swis Prot.: Q9NRC8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions.
Alternative Name:
NAD dependent deacetylase sirtuin 7, NAD-dependent deacetylase sirtuin-7, Silent mating type information regulation 2 homolog, Silent mating type information regulation 2 S.cerevisiae homolog 7, IR2 L7, SIR2 like protein 7, Sir2 related protein type 7, SIR2, S.CEREVISIAE, HOMOLOG-LIKE 7, SIR2-like protein 7, SIR2L 7, SIR2L7, SIRT 7, SIRT7, SIRT7, Sirtuin 7, Sirtuin type 7, Sirtuin7,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: SIRT7 polyclonal antibody detects endogenous levels of SIRT7 protein.
Immunogen:
Recombinant full length Human SIRT7.
MW: ~ 44 kDa
Swis Prot.: Q9NRC8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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