SLC12A1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12325a
Background:
This gene encodes a kidney-specificsodium-potassium-chloride cotransporter that is expressed on theluminal membrane of renal epithelial cells of the thick ascendinglimb of Henle's loop and the macula densa. It plays a key role inconcentrating urine and accounts for most of the NaCl resorption.It is sensitive to such diuretics as furosemide and bumetanide.Some Bartter-like syndromes result from defects in this gene.Alternative splicing results in multiple transcript variantsencoding distinct isoforms. Additional splice variants have beendescribed but their biological validity in humans has not beenexperimentally proven.
Other Names:
Solute carrier family 12 member 1, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, Kidney-specific Na-K-Cl symporter, SLC12A1, NKCC2
Gene Name: SLC12A1
Gene ID: 6557
Primary Accession: Q13621
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a kidney-specificsodium-potassium-chloride cotransporter that is expressed on theluminal membrane of renal epithelial cells of the thick ascendinglimb of Henle's loop and the macula densa. It plays a key role inconcentrating urine and accounts for most of the NaCl resorption.It is sensitive to such diuretics as furosemide and bumetanide.Some Bartter-like syndromes result from defects in this gene.Alternative splicing results in multiple transcript variantsencoding distinct isoforms. Additional splice variants have beendescribed but their biological validity in humans has not beenexperimentally proven.
Other Names:
Solute carrier family 12 member 1, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2, Kidney-specific Na-K-Cl symporter, SLC12A1, NKCC2
Gene Name: SLC12A1
Gene ID: 6557
Primary Accession: Q13621
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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