SLC1A2 antibody (clone 4G8), anti-human
€435.00
In stock
SKU
AC-AT3906a
Catalog Number: AC-AT3906a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3906a">Request Information
Background:
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Other Names:
Excitatory amino acid transporter 2, Glutamate/aspartate transporter II, Sodium-dependent glutamate/aspartate transporter 2, Solute carrier family 1 member 2, SLC1A2, EAAT2, GLT1
Antigen Type:
Recombinant Protein
Gene Name: SLC1A2 (HGNC:10940)
Gene ID: 6506
NCBI Accession: NP_001182657.1;NP_001239581.1;NP_004162.2
Primary Accession: P43004
Other Accession: NM_004171
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Other Names:
Excitatory amino acid transporter 2, Glutamate/aspartate transporter II, Sodium-dependent glutamate/aspartate transporter 2, Solute carrier family 1 member 2, SLC1A2, EAAT2, GLT1
Antigen Type:
Recombinant Protein
Gene Name: SLC1A2 (HGNC:10940)
Gene ID: 6506
NCBI Accession: NP_001182657.1;NP_001239581.1;NP_004162.2
Primary Accession: P43004
Other Accession: NM_004171
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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