SLC1A4 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7488
Background:
SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine (1). SLC1A4 mediates the efflux of glutamate from the neuron into the synaptic junction via calcium-independent release, as well as mediating the efflux of L-serine from glial cells and its uptake by neurons (2). SLC1A4-mediated transport is shown to involve a symmetrical potassium-independent electroneutral exchange of neutral amino acids and sodium, such that the current activated during transport is carried only by chloride ions (3).
Alternative Name:
Alanine/serine/cysteine/threonine transporter 1, ASCT-1, ASCT1, AW045657, Glutamate/neutral amino acid transporter, Neutral amino acid transporter A, OTTHUMP00000159933, OTTHUMP00000235138, SATT, SATT_HUMAN, SLC1A4, Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, Solute carrier family 1 member 4,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SLC1A4 polyclonal antibody detects endogenous levels of SLC1A4 protein.
Immunogen:
Recombinant full length Human SLC1A4.
MW: ~56 kDa
Swis Prot.: P43007
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine (1). SLC1A4 mediates the efflux of glutamate from the neuron into the synaptic junction via calcium-independent release, as well as mediating the efflux of L-serine from glial cells and its uptake by neurons (2). SLC1A4-mediated transport is shown to involve a symmetrical potassium-independent electroneutral exchange of neutral amino acids and sodium, such that the current activated during transport is carried only by chloride ions (3).
Alternative Name:
Alanine/serine/cysteine/threonine transporter 1, ASCT-1, ASCT1, AW045657, Glutamate/neutral amino acid transporter, Neutral amino acid transporter A, OTTHUMP00000159933, OTTHUMP00000235138, SATT, SATT_HUMAN, SLC1A4, Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, Solute carrier family 1 member 4,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SLC1A4 polyclonal antibody detects endogenous levels of SLC1A4 protein.
Immunogen:
Recombinant full length Human SLC1A4.
MW: ~56 kDa
Swis Prot.: P43007
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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