SLC26A5 antibody (clone 1F4), anti-human
€435.00
In stock
SKU
AC-AT3916a
Catalog Number: AC-AT3916a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT3916a">Request Information
Background:
This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Prestin, Solute carrier family 26 member 5, SLC26A5, PRES
Antigen Type:
Recombinant Protein
Gene Name: SLC26A5 (HGNC:9359)
Gene ID: 375611
NCBI Accession: NP_001161434.1;NP_945350.1;NP_996766.1;NP_996767.1;NP_996768.1
Primary Accession: P58743
Other Accession: NM_198999
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Prestin, Solute carrier family 26 member 5, SLC26A5, PRES
Antigen Type:
Recombinant Protein
Gene Name: SLC26A5 (HGNC:9359)
Gene ID: 375611
NCBI Accession: NP_001161434.1;NP_945350.1;NP_996766.1;NP_996767.1;NP_996768.1
Primary Accession: P58743
Other Accession: NM_198999
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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