SLC28A2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5670
Background:
The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.
Alternative Name:
Sodium/nucleoside cotransporter 2, Concentrative nucleoside transporter 2, CNT 2, hCNT2, Na(+)/nucleoside cotransporter 2, Sodium-coupled nucleoside transporter 2, Sodium/purine nucleoside co-transporter, SPNT, Solute carrier family 28 member 2, CNT2, CNT-2
Application Dilution: WB: 1:500~1:1000
Specificity: SLC28A2 polyclonal antibody detects endogenous levels of SLC28A2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 417-462 of Human SLC28A2.
MW: ~ 72 kDa
Swis Prot.: O43868
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.
Alternative Name:
Sodium/nucleoside cotransporter 2, Concentrative nucleoside transporter 2, CNT 2, hCNT2, Na(+)/nucleoside cotransporter 2, Sodium-coupled nucleoside transporter 2, Sodium/purine nucleoside co-transporter, SPNT, Solute carrier family 28 member 2, CNT2, CNT-2
Application Dilution: WB: 1:500~1:1000
Specificity: SLC28A2 polyclonal antibody detects endogenous levels of SLC28A2 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 417-462 of Human SLC28A2.
MW: ~ 72 kDa
Swis Prot.: O43868
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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