SLC6A4 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS72445
Background:
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Alternative Name:
5-HTT,5-HTTLPR,5HTT,hSERT,HTT,OCD1,SERT,SERT1
Application Dilution: WB: 1:500 - 1:2000
Specificity: SLC6A4 polyclonal antibody detects endogenous levels of SLC6A4 protein.
Immunogen:
A synthetic peptide of human SLC6A4
MW: ~ 69 kDa
Swis Prot.: P31645
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Alternative Name:
5-HTT,5-HTTLPR,5HTT,hSERT,HTT,OCD1,SERT,SERT1
Application Dilution: WB: 1:500 - 1:2000
Specificity: SLC6A4 polyclonal antibody detects endogenous levels of SLC6A4 protein.
Immunogen:
A synthetic peptide of human SLC6A4
MW: ~ 69 kDa
Swis Prot.: P31645
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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