SLC6A5 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71708
Background:
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
NET1, GLYT2, HKPX3, GLYT-2
Application Dilution: WB : 1:500 - 1:2000
Specificity: SLC6A5 polyclonal antibody detects endogenous levels of SLC6A5 protein.
Immunogen:
Recombinant protein of human SLC6A5
MW: Predicted band size: 87 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9Y345
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
NET1, GLYT2, HKPX3, GLYT-2
Application Dilution: WB : 1:500 - 1:2000
Specificity: SLC6A5 polyclonal antibody detects endogenous levels of SLC6A5 protein.
Immunogen:
Recombinant protein of human SLC6A5
MW: Predicted band size: 87 kDa, Observed band size: Refer to Figures
Swis Prot.: Q9Y345
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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