SLC8A1 (clone 6H2), anti-human, mouse, rat, rabbit
€510.00
In stock
SKU
253215
Protein Family: Receptors and Channels
Pathway and Disease: Signal Transduction
Description:
Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling. NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury.
Alternate Names: Sodium/calcium exchanger 1, Na(+)/Ca(2+)-exchange protein 1, Slc8a1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: Q01728
Antigen: KLH-conjugated peptide encompassing a sequence within the N-term region of rabbit sodium calcium exchanger 1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signal Transduction
Description:
Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintenance of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling. NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury.
Alternate Names: Sodium/calcium exchanger 1, Na(+)/Ca(2+)-exchange protein 1, Slc8a1
Application Notes: E: 1:500-1:1,000; WB: 1:1,000
Accession No.: Q01728
Antigen: KLH-conjugated peptide encompassing a sequence within the N-term region of rabbit sodium calcium exchanger 1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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