SLC9A8 polyclonal, anti-human
€305.00
In stock
SKU
BS61730
Background:
Na+/H+ exchangers 1-8, also designated Na+/H+ antiporters or NHE-1-8, are integral membrane proteins expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, NHE isoforms 2-8 have distinct tissue and cell type dependent expression and inhibitory characteristics. NHE-8 is a 575 amino acid protein that localizes apically in intestinal epithelial cells. Expression of NHE-8 is higher in young mammals than adults. NHE-8 gene and protein expression are highly regulated during ontogeny; this protein may play an important role in intestinal Na+ absorption during early mammalian life.
Alternative Name:
Sodium/hydrogen exchanger 8, Na(+)/H(+) exchanger 8, NHE-8, Solute carrier family 9 member 8, SLC9A8, KIAA0939, NHE8
Application Dilution: WB: 1:500~1:1000
Specificity: SLC9A8 polyclonal antibody detects endogenous levels of SLC9A8 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 450-500 of Human SLC9A8.
MW: ~ 65 kDa
Swis Prot.: Q9Y2E8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Na+/H+ exchangers 1-8, also designated Na+/H+ antiporters or NHE-1-8, are integral membrane proteins expressed in most mammalian tissues where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, NHE isoforms 2-8 have distinct tissue and cell type dependent expression and inhibitory characteristics. NHE-8 is a 575 amino acid protein that localizes apically in intestinal epithelial cells. Expression of NHE-8 is higher in young mammals than adults. NHE-8 gene and protein expression are highly regulated during ontogeny; this protein may play an important role in intestinal Na+ absorption during early mammalian life.
Alternative Name:
Sodium/hydrogen exchanger 8, Na(+)/H(+) exchanger 8, NHE-8, Solute carrier family 9 member 8, SLC9A8, KIAA0939, NHE8
Application Dilution: WB: 1:500~1:1000
Specificity: SLC9A8 polyclonal antibody detects endogenous levels of SLC9A8 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 450-500 of Human SLC9A8.
MW: ~ 65 kDa
Swis Prot.: Q9Y2E8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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