SMA (clone 1A4), anti-human, mouse, rat

SMA (clone 1A4), anti-human, mouse, rat

€445.00
In stock
SKU
251813
Catalog Nr.: 251813
Size: 0.1 mg
Isotype: Mouse IgG2a
Applications: E, WB, IHC
Datasheet
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Protein Family: Cytoskeleton Proteins

Pathway and Disease: Cell Communication, Cell Motility

Description:
Alpha-actin-2 (ACTA2), the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. Alpha-actins are a major constituent of the contractile apparatus. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6, characterized by permanent dilation of the thoracic aorta.

Alternate Names: Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTA2, ACTSA, ACTVS

Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections and formalin-fixed paraffin tissues. E: 0.5-1 ug/ml; WB: 1-2 ug/ml; IHC: 0.5-1 ug/ml

Accession No.: P62736

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SMA.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.2% BSA with 0.09% sodium azide. Antibody was purified by anti-mouse IgG affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
Zhu X et al. 2014. Oncogene. 33(15): 1986-96. PMID# 23604117
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