SMARCAD1 polyclonal, anti-human, mouse, rat

SMARCAD1 polyclonal, anti-human, mouse, rat

€388.00
In stock
SKU
BS7898
Catalog Number: BS7898
Size: 50 ul, 100 ul
Isotype: rabbit IgG
Applications: WB, IHC, IF

Datasheet
Background:
Smarcad1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1), also known as ETL1 or HEL1, is a 1,026 amino acid nuclear protein suggested to function as an ATPdependent DNA helicase. A member of the SNF2/RAD54 helicase family, Smarcad1 undergoes post-translational phosphorylation by either ATM or ATR and contains one helicase C-terminal domain, a helicase ATP-binding domain and two CUE domains. Existing as two alternatively spliced isoforms, Smarcad1 is encoded by a gene that maps to human chromosome 4, which represents approximately 6% of the human genome, contains nearly 900 genes and is associated with Huntington’s disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Alternative Name:
ATP dependent helicase 1, ATP-dependent helicase 1, ETL1, hHEL1, Smarcad1, SMRCD_HUMAN, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containingDEAD/H box 1,

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100

Specificity: SMARCAD1 polyclonal antibody detects endogenous levels of SMARCAD1 protein.

Immunogen:
Recombinant full length Human SMARCAD1.

MW: ~ 90, 117 kDa

Swis Prot.: Q9H4L7

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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