SMARCB1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7846
Background:
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
Alternative Name:
BAF47, BRG1-associated factor 47, hSNF5, INI1, Integrase interactor 1 protein, Malignant rhabdoid tumor suppressor, RDT, RTPS1, Sfh1p, SMARCB1, SNF5 homolog, SNF5_HUMAN, SNF5L1, Snr1, Sucrose nonfermenting yeast homolog like 1, SWI/SNF complex component SNF5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, SWI10, Transcription factor TYE4, Transcription regulatory protein SNF5, TYE4,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SMARCB1 polyclonal antibody detects endogenous levels of SMARCB1 protein.
Immunogen:
Recombinant full length Human SMARCB1.
MW: ~ 44 kDa
Swis Prot.: Q12824
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
Alternative Name:
BAF47, BRG1-associated factor 47, hSNF5, INI1, Integrase interactor 1 protein, Malignant rhabdoid tumor suppressor, RDT, RTPS1, Sfh1p, SMARCB1, SNF5 homolog, SNF5_HUMAN, SNF5L1, Snr1, Sucrose nonfermenting yeast homolog like 1, SWI/SNF complex component SNF5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, SWI10, Transcription factor TYE4, Transcription regulatory protein SNF5, TYE4,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SMARCB1 polyclonal antibody detects endogenous levels of SMARCB1 protein.
Immunogen:
Recombinant full length Human SMARCB1.
MW: ~ 44 kDa
Swis Prot.: Q12824
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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