SMARCE1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome.

Alternative Name:
BAF57, BRG1 associated factor 57, BRG1-associated factor 57, Chromatin remodeling complex BRG1 associated factor 57, FLJ35648, SMARCE 1, SMARCE1, SMCE1_HUMAN, SWI/SNF related matrix associated actin dependent regulator of chromatin e1, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily e member 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1,

Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200, IP/CHIP: 1:50~1:200

Specificity: SMARCE1 polyclonal antibody detects endogenous levels of SMARCE1 protein.

Immunogen:
Recombinant full length Human SMARCE1.

MW: ~46 kDa

Swis Prot.: Q969G3

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.