SMC3 Picoband™ (clone 4C12), anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO14780
Catalog Number: AC-ABO14780
Size: 100 µg
Isotype: Mouse
Applications: WB, IHC
Datasheet
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Size: 100 µg
Isotype: Mouse
Applications: WB, IHC
Datasheet
Request Information
Description: Anti-SMC3 Antibody Picoband™ (monoclonal, 4C12) . Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Other Names: Structural maintenance of chromosomes protein 3, SMC protein 3, SMC-3, Basement membrane-associated chondroitin proteoglycan, Bamacan, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, hCAP, SMC3, BAM, BMH, CSPG6, SMC3L1
Clone Name(s):
Clone: 4C12
Subcellular Localization: Nucleus
Gene ID: 9126
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SMC3, identical to the related mouse sequence.
Calculated MW: 141542
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Protein Function:
Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement.
Other Names: Structural maintenance of chromosomes protein 3, SMC protein 3, SMC-3, Basement membrane-associated chondroitin proteoglycan, Bamacan, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, hCAP, SMC3, BAM, BMH, CSPG6, SMC3L1
Clone Name(s):
Clone: 4C12
Subcellular Localization: Nucleus
Gene ID: 9126
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SMC3, identical to the related mouse sequence.
Calculated MW: 141542
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Concentration (mg/ml): Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.
Storage: Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
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