SNAI1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8479
Background:
The Snail family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. The Snail-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription.
Alternative Name:
Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna, SNAI1, SNAH, SNAI 1, Snail 1, Snail-1
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SNAI1 polyclonal antibody detects endogenous levels of SNAI1 protein.
Immunogen:
Recombinant full length Human SNAI1.
MW: ~ 29kDa
Swis Prot.: O95863
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Snail family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver, and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. The Snail-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription.
Alternative Name:
Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna, SNAI1, SNAH, SNAI 1, Snail 1, Snail-1
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: SNAI1 polyclonal antibody detects endogenous levels of SNAI1 protein.
Immunogen:
Recombinant full length Human SNAI1.
MW: ~ 29kDa
Swis Prot.: O95863
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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