SNAP23 antibody (clone 2F5-3D4), anti-human
€435.00
In stock
SKU
AC-AT3971a
Catalog Number: AC-AT3971a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IP, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IP, E
Request Information AC-AT3971a">Request Information
Background:
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Other Names:
Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23, SNAP23
Antigen Type:
Recombinant Protein
Gene Name: SNAP23
Gene ID: 8773
NCBI Accession: NP_003816.2;NP_570710.1
Primary Accession: O00161
Other Accession: BC000148
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Other Names:
Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23, SNAP23
Antigen Type:
Recombinant Protein
Gene Name: SNAP23
Gene ID: 8773
NCBI Accession: NP_003816.2;NP_570710.1
Primary Accession: O00161
Other Accession: BC000148
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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