SNRNP70 polyclonal, anti-human, mouse, rat

Background:
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.

Alternative Name:
U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, U1-70K, snRNP70, RNPU1Z, RPU1, SNRP70, U1AP1

Application Dilution: WB: 1:500 - 1:1000, IHC: 1:50 - 1:100

Specificity: SNRNP70 polyclonal antibody detects endogenous levels of SNRNP70 protein.

Immunogen:
A synthetic peptide of human SNRNP70.

MW: ~ 70 kDa

Swis Prot.: P08621

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.