SNW1 polyclonal, anti-human
€388.00
In stock
SKU
BS72665
Background:
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Alternative Name:
Bx42,FUN20,NCOA-62,Prp45,PRPF45,SKIIP,SKIP,SKIP1,Bx42,NCOA-62,Prp45,PRPF45,SKIIP,SKIP
Application Dilution: WB: 1:500 - 1:2000
Specificity: SNW1 polyclonal antibody detects endogenous levels of SNW1 protein.
Immunogen:
Recombinant protein of human SNW1
MW: Refer to Figures
Swis Prot.: Q13573
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. Alternative splicing results in multiple transcript variants.
Alternative Name:
Bx42,FUN20,NCOA-62,Prp45,PRPF45,SKIIP,SKIP,SKIP1,Bx42,NCOA-62,Prp45,PRPF45,SKIIP,SKIP
Application Dilution: WB: 1:500 - 1:2000
Specificity: SNW1 polyclonal antibody detects endogenous levels of SNW1 protein.
Immunogen:
Recombinant protein of human SNW1
MW: Refer to Figures
Swis Prot.: Q13573
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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