GPR75 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP70213
Background:
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Other Names:
GPR75; Probable G-protein coupled receptor 75
Antigen Type: synthetic peptide
Antigen Type: GPR75
Gene ID: 10936
Primary Accession: O95800
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Other Names:
GPR75; Probable G-protein coupled receptor 75
Antigen Type: synthetic peptide
Antigen Type: GPR75
Gene ID: 10936
Primary Accession: O95800
| Is Featured? | No |
|---|
Write Your Own Review