SOAT1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS8121
Background:
SOAT1 (sterol O-acyltransferase-1), also designated ACAT1, is a homotetra-meric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A (acyl-CoA). The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol O-acyltransferase-2), also known as ACAT2 (acyl-CoA:cholesterol acyltransferase-2), participates in lipo-protein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.
Alternative Name:
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1, SOAT1, ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT
Application Dilution: WB: 1:500 - 1:2000
Specificity: SOAT1 polyclonal antibody detects endogenous levels of SOAT1 protein.
Immunogen:
Recombinant full length Human SOAT1.
MW: ~ 65 kDa
Swis Prot.: P35610
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SOAT1 (sterol O-acyltransferase-1), also designated ACAT1, is a homotetra-meric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A (acyl-CoA). The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol O-acyltransferase-2), also known as ACAT2 (acyl-CoA:cholesterol acyltransferase-2), participates in lipo-protein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.
Alternative Name:
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1, SOAT1, ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT
Application Dilution: WB: 1:500 - 1:2000
Specificity: SOAT1 polyclonal antibody detects endogenous levels of SOAT1 protein.
Immunogen:
Recombinant full length Human SOAT1.
MW: ~ 65 kDa
Swis Prot.: P35610
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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