SOCS3 (clone 3A10A12), anti-human
€0.00
In stock
SKU
BT-MCA4370
Catalog Number: BT-MCA4370
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC, ICC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC, ICC, FCM
Datasheet
Request Information
Background:
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Research Area: Signal transduction, Epigenetics and nuclear signaling, Cancer, Stem cells, Metabolism, Immunology
Synonyms: CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3
Immunogen: Purified recombinant fragment of human SOCS3 (AA: full(1-225)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
Research Area: Signal transduction, Epigenetics and nuclear signaling, Cancer, Stem cells, Metabolism, Immunology
Synonyms: CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3
Immunogen: Purified recombinant fragment of human SOCS3 (AA: full(1-225)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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