SORD antibody (clone 4D3), anti-human, mouse, rat
€435.00
In stock
SKU
AC-AT3993a
Catalog Number: AC-AT3993a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, Ehttps://www.abcepta.com/products/pdf_download/AT3993a-SORD-Antibody-monoclonal-M01">Request Information AC-AT3993a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, Ehttps://www.abcepta.com/products/pdf_download/AT3993a-SORD-Antibody-monoclonal-M01">Request Information AC-AT3993a">Request Information
Background:
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Other Names:
Sorbitol dehydrogenase, L-iditol 2-dehydrogenase, SORD
Antigen Type:
Recombinant Protein
Gene Name: SORD
Gene ID: 6652
NCBI Accession: NP_003095.2
Primary Accession: Q00796
Other Accession: NM_003104
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Other Names:
Sorbitol dehydrogenase, L-iditol 2-dehydrogenase, SORD
Antigen Type:
Recombinant Protein
Gene Name: SORD
Gene ID: 6652
NCBI Accession: NP_003095.2
Primary Accession: Q00796
Other Accession: NM_003104
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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