SORL1 polyclonal, anti-human
€388.00
In stock
SKU
BS72190
Background:
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.
Alternative Name:
C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
Application Dilution: WB: 1:500 - 1:2000
Specificity: SORL1 polyclonal antibody detects endogenous levels of SORL1 protein.
Immunogen:
Recombinant Protein of human SORL1
MW: 290kDa
Swis Prot.: Q92673
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.
Alternative Name:
C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
Application Dilution: WB: 1:500 - 1:2000
Specificity: SORL1 polyclonal antibody detects endogenous levels of SORL1 protein.
Immunogen:
Recombinant Protein of human SORL1
MW: 290kDa
Swis Prot.: Q92673
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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