SORT1 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP11584c
Background:
This gene encodes a protein that is a multi-ligand type-1receptor with similarity to the yeast carboxypeptidase Y sortingreceptor Vps10 protein. The encoded protein, a trans-Golgi network(TGN) transmembrane protein, binds a number of unrelated ligandsthat participate in a wide range of cellular processes; however, itlacks the typical features of a signalling receptor. In the TGN,furin mediates the activation of the mature binding form. Theencoded protein consists of a large luminal domain, a singletransmembrane segment and short C-terminal cytoplasmic tail. Theluminal domain contains a cysteine-rich region similar to twocorresponding segments in the yeast Vps10p; the cytoplasmic tail issimilar to the corresponding segment of the cation-independentmannose 6-phosphate receptor and the tail also interacts with theVHS domains of GGA (Golgi-associated, gamma-adaptin homologous,ARF-interacting) proteins.
Other Names:
Sortilin, 100 kDa NT receptor, Glycoprotein 95, Gp95, Neurotensin receptor 3, NT3, NTR3, SORT1
Gene Name: SORT1 (HGNC:11186)
Gene ID: 6272
Primary Accession: Q99523
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a protein that is a multi-ligand type-1receptor with similarity to the yeast carboxypeptidase Y sortingreceptor Vps10 protein. The encoded protein, a trans-Golgi network(TGN) transmembrane protein, binds a number of unrelated ligandsthat participate in a wide range of cellular processes; however, itlacks the typical features of a signalling receptor. In the TGN,furin mediates the activation of the mature binding form. Theencoded protein consists of a large luminal domain, a singletransmembrane segment and short C-terminal cytoplasmic tail. Theluminal domain contains a cysteine-rich region similar to twocorresponding segments in the yeast Vps10p; the cytoplasmic tail issimilar to the corresponding segment of the cation-independentmannose 6-phosphate receptor and the tail also interacts with theVHS domains of GGA (Golgi-associated, gamma-adaptin homologous,ARF-interacting) proteins.
Other Names:
Sortilin, 100 kDa NT receptor, Glycoprotein 95, Gp95, Neurotensin receptor 3, NT3, NTR3, SORT1
Gene Name: SORT1 (HGNC:11186)
Gene ID: 6272
Primary Accession: Q99523
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review