NF-E4 (Acetyl Lys43) polyclonal, anti-human
€470.00
In stock
SKU
AC-AP63246
Catalog Number: AC-AP72553
Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
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Size: 100 µl
Host: Rabbit
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
Other Names:
NFE4; Transcription factor NF-E4
Antigen Type: synthetic peptide
Antigen Type: NFE4
Primary Accession: Q86UQ8
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
Other Names:
NFE4; Transcription factor NF-E4
Antigen Type: synthetic peptide
Antigen Type: NFE4
Primary Accession: Q86UQ8
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