SOX17 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61556
Background:
Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects.
Alternative Name:
Transcription factor SOX-17
Application Dilution: WB: 1:500~1:1000
Specificity: SOX17 polyclonal antibody detects endogenous levels of SOX17 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 121-165 of Human SOX17
MW: ~ 48 kDa
Swis Prot.: Q9H6I2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects.
Alternative Name:
Transcription factor SOX-17
Application Dilution: WB: 1:500~1:1000
Specificity: SOX17 polyclonal antibody detects endogenous levels of SOX17 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 121-165 of Human SOX17
MW: ~ 48 kDa
Swis Prot.: Q9H6I2
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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