Sox2 (clone ), anti-human, mouse
€388.00
In stock
SKU
MB0064
Background:
SOX 2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX 2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.
Alternative Name:
Transcription factor SOX-2
Application Dilution: WB: 1:1000, ICC: 1:50~200, FC: 1:50~100
Specificity: This antibody detects endogenous levels of Sox2 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human Sox2.
MW: Predicted band size: 35KDa, Observed band size: 35KDa
Swis Prot.: P48431
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SOX 2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX 2 is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206.
Alternative Name:
Transcription factor SOX-2
Application Dilution: WB: 1:1000, ICC: 1:50~200, FC: 1:50~100
Specificity: This antibody detects endogenous levels of Sox2 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human Sox2.
MW: Predicted band size: 35KDa, Observed band size: 35KDa
Swis Prot.: P48431
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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