SOX4 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2045a
Background:
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
Other Names:
Transcription factor SOX-4, SOX4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2045a was selected from the N-term region of human SOX4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SOX4 {ECO:0000303|PubMed:8268656, ECO:0000312|HGNC:HGNC:11200}
Gene ID: 6659
Primary Accession: Q06945
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.
Other Names:
Transcription factor SOX-4, SOX4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2045a was selected from the N-term region of human SOX4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SOX4 {ECO:0000303|PubMed:8268656, ECO:0000312|HGNC:HGNC:11200}
Gene ID: 6659
Primary Accession: Q06945
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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