SPAK (STK39) Antibody (C-term) Blocking peptide

SPAK (STK39) Antibody (C-term) Blocking peptide

€363.00
In stock
SKU
AC-BP1448b
Catalog Number: AC-BP1448b
Size: 500 µg
Datasheet
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Background:
STK39 is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Other Names:
STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP1448b was selected from the C-term region of human STK39. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: STK39

Gene ID: 27347
Primary Accession: Q9UEW8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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