SPAST antibody (clone 2F5), anti-human
€435.00
In stock
SKU
AC-AT4016a
Catalog Number: AC-AT4016a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF
Request Information AC-AT4016a">Request Information
Background:
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
Other Names:
Spastin {ECO:0000255|HAMAP-Rule:MF_03021}, 3643 {ECO:0000255|HAMAP-Rule:MF_03021}, Spastic paraplegia 4 protein, SPAST {ECO:0000255|HAMAP-Rule:MF_03021}
Antigen Type:
Recombinant Protein
Gene Name: SPAST {ECO:0000255|HAMAP-Rule:MF_03021, ECO:0000312|HGNC:HGNC:11233}
Gene ID: 6683
NCBI Accession: NP_055761.2;NP_955468.1
Primary Accession: Q9UBP0
Other Accession: NM_014946
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
Other Names:
Spastin {ECO:0000255|HAMAP-Rule:MF_03021}, 3643 {ECO:0000255|HAMAP-Rule:MF_03021}, Spastic paraplegia 4 protein, SPAST {ECO:0000255|HAMAP-Rule:MF_03021}
Antigen Type:
Recombinant Protein
Gene Name: SPAST {ECO:0000255|HAMAP-Rule:MF_03021, ECO:0000312|HGNC:HGNC:11233}
Gene ID: 6683
NCBI Accession: NP_055761.2;NP_955468.1
Primary Accession: Q9UBP0
Other Accession: NM_014946
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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