SPDYA polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6810
Background:
Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
Alternative Name:
hSpy/Ringo A, MGC110856, MGC57218, OTTHUMP00000082662, OTTHUMP00000082663, OTTHUMP00000082664, Rapid inducer of G2/M progression in oocytes A, RINGO A, RINGO3, SPDY1, Speedy A, Speedy homolog 1 (Drosophila), Speedy homolog A (Xenopus laevis), Speedy homolog A, Speedy-1, SPY1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: SPDYA polyclonal antibody detects endogenous levels of SPDYA protein.
Immunogen:
Recombinant full length Human SPDYA.
MW: ~ 36 kDa
Swis Prot.: Q5MJ70
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome.
Alternative Name:
hSpy/Ringo A, MGC110856, MGC57218, OTTHUMP00000082662, OTTHUMP00000082663, OTTHUMP00000082664, Rapid inducer of G2/M progression in oocytes A, RINGO A, RINGO3, SPDY1, Speedy A, Speedy homolog 1 (Drosophila), Speedy homolog A (Xenopus laevis), Speedy homolog A, Speedy-1, SPY1,
Application Dilution: WB: 1:500 - 1:2000
Specificity: SPDYA polyclonal antibody detects endogenous levels of SPDYA protein.
Immunogen:
Recombinant full length Human SPDYA.
MW: ~ 36 kDa
Swis Prot.: Q5MJ70
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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