Spectrin alpha/beta (clone Spe 1/2), anti-human
€445.00
In stock
SKU
251797
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Signaling Molecules and Interaction
Description:
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. Spectrin associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Defects in spectrin are the cause of elliptocytosis type 2 (EL2). EL2 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. EL2 is characterized by variable hemolytic anemia and elliptical or oval red cell shape.
Alternate Names: Spectrin alpha chain, erythrocyte, Erythroid alpha-spectrin, SPTA1, SPTA, Spectrin beta chain, erythrocyte, Beta-I spectrin, SPTB, SPTB1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P02549; P11277
Antigen: Human erythrocyte spectrin
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. Spectrin associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Defects in spectrin are the cause of elliptocytosis type 2 (EL2). EL2 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. EL2 is characterized by variable hemolytic anemia and elliptical or oval red cell shape.
Alternate Names: Spectrin alpha chain, erythrocyte, Erythroid alpha-spectrin, SPTA1, SPTA, Spectrin beta chain, erythrocyte, Beta-I spectrin, SPTB, SPTB1
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P02549; P11277
Antigen: Human erythrocyte spectrin
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
| Is Featured? | No |
|---|
Write Your Own Review