SPHK1 Antibody (C-term R414) Blocking Peptide
€363.00
In stock
SKU
AC-BP7237b
Background:
SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
Other Names:
Sphingosine kinase 1, SK 1, SPK 1, SPHK1, SPHK, SPK
Gene Name: SPHK1 (HGNC:11240)
Gene ID: 8877
Primary Accession: Q9NYA1
Other Accession: Q8N632
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
Other Names:
Sphingosine kinase 1, SK 1, SPK 1, SPHK1, SPHK, SPK
Gene Name: SPHK1 (HGNC:11240)
Gene ID: 8877
Primary Accession: Q9NYA1
Other Accession: Q8N632
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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