SPHK1 polyclonal, anti-human, mouse, rat

Background:
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.

Alternative Name:
SK 1, SK1, Sphingosine Kinase 1, SPHK 1, SPHK, Sphk1, SPHK1, SPK, SPK 1, SPK1,

Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200

Specificity: SPHK1 polyclonal antibody detects endogenous levels of SPHK1 protein.

Immunogen:
Recombinant full length Human SPHK1.

MW: ~ 43 kDa

Swis Prot.: Q9NYA1

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.