SPP Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6314a
Background:
SPP, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. This protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases.
Other Names:
Minor histocompatibility antigen H13, 3423-, Intramembrane protease 1, IMP-1, IMPAS-1, hIMP1, Presenilin-like protein 3, Signal peptide peptidase, HM13, H13, IMP1, PSL3, SPP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6314a was selected from the N-term region of human SPP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HM13
Gene ID: 81502
Primary Accession: Q8TCT9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
SPP, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. This protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases.
Other Names:
Minor histocompatibility antigen H13, 3423-, Intramembrane protease 1, IMP-1, IMPAS-1, hIMP1, Presenilin-like protein 3, Signal peptide peptidase, HM13, H13, IMP1, PSL3, SPP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6314a was selected from the N-term region of human SPP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: HM13
Gene ID: 81502
Primary Accession: Q8TCT9
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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