SPPL3 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6313a
Background:
Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.
Other Names:
Signal peptide peptidase-like 3, SPP-like 3, 3423-, Intramembrane protease 2, IMP-2, Presenilin homologous protein 1, PSH1, Presenilin-like protein 4, SPPL3, IMP2, PSL4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6313a was selected from the N-term region of human SPPL3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SPPL3 {ECO:0000303|PubMed:12077416, ECO:0000312|HGNC:HGNC:30424}
Gene ID: 121665
Primary Accession: Q8TCT6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Signal peptide peptidase (SPP) is an aspartyl protease that mediates clearance of signal peptides by proteolysis within the endoplasmic reticulum (ER). Like presenilins, SPP contains a critical GXGD motif in its C-terminal catalytic center. SPPL3 is one of several presenilin homologues/SPP-like proteins (PSHs/SPPL) that have been identified.
Other Names:
Signal peptide peptidase-like 3, SPP-like 3, 3423-, Intramembrane protease 2, IMP-2, Presenilin homologous protein 1, PSH1, Presenilin-like protein 4, SPPL3, IMP2, PSL4
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6313a was selected from the N-term region of human SPPL3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: SPPL3 {ECO:0000303|PubMed:12077416, ECO:0000312|HGNC:HGNC:30424}
Gene ID: 121665
Primary Accession: Q8TCT6
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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