SPRY2 antibody (clone 10000000000), anti-human
€435.00
In stock
SKU
AC-AT4032a
Catalog Number: AC-AT4032a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT4032a">Request Information
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT4032a">Request Information
Background:
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
Other Names:
Protein sprouty homolog 2, Spry-2, SPRY2
Antigen Type:
Recombinant Protein
Gene Name: SPRY2
Gene ID: 10253
NCBI Accession: NP_005833.1
Primary Accession: O43597
Other Accession: BC015745
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
Other Names:
Protein sprouty homolog 2, Spry-2, SPRY2
Antigen Type:
Recombinant Protein
Gene Name: SPRY2
Gene ID: 10253
NCBI Accession: NP_005833.1
Primary Accession: O43597
Other Accession: BC015745
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review