SPTLC2 Blocking Peptide (Center)

Background:
This gene encodes a long chain base subunit of serinepalmitoyltransferase. Serine palmitoyltransferase, which consistsof two different subunits, is the key enzyme in sphingolipidbiosynthesis. It catalyzes thepyridoxal-5-prime-phosphate-dependent condensation of L-serine andpalmitoyl-CoA to 3-oxosphinganine. Mutations in this gene wereidentified in patients with hereditary sensory neuropathy type I.Alternatively spliced variants encoding different isoforms havebeen identified.

Other Names:
Serine palmitoyltransferase 2, Long chain base biosynthesis protein 2, LCB 2, Long chain base biosynthesis protein 2a, LCB2a, Serine-palmitoyl-CoA transferase 2, SPT 2, SPTLC2, KIAA0526, LCB2

Target/Specificity:
The synthetic peptide sequence is selected from aa 387-401 of HUMAN SPTLC2

Gene Name: SPTLC2 (HGNC:11278)

Gene ID: 9517
Primary Accession: O15270
Other Accession: P97363; NP_004854.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.