SQLE polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71537
Background:
SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
Alternative Name:
FLJ30795, Squalene monooxygenase,SQLE,ERG1,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SQLE polyclonal antibody detects endogenous levels of SQLE protein.
Immunogen:
Recombinant protein of human SQLE
MW: Predicted band size: 64 kDa, Observed band size: Refer to Figures
Swis Prot.: Q14534
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
Alternative Name:
FLJ30795, Squalene monooxygenase,SQLE,ERG1,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: SQLE polyclonal antibody detects endogenous levels of SQLE protein.
Immunogen:
Recombinant protein of human SQLE
MW: Predicted band size: 64 kDa, Observed band size: Refer to Figures
Swis Prot.: Q14534
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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