SQSTM1 antibody (clone 2C11), anti-human, mouse
€435.00
In stock
SKU
AC-AT4033a
Catalog Number: AC-AT4033a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IF, Ehttps://www.abcepta.com/products/pdf_download/AT4033a-SQSTM1-Antibody-monoclonal-M01">Request Information AC-AT4033a">Request Information
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IF, Ehttps://www.abcepta.com/products/pdf_download/AT4033a-SQSTM1-Antibody-monoclonal-M01">Request Information AC-AT4033a">Request Information
Background:
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Other Names:
Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP, p60, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, SQSTM1, ORCA, OSIL
Antigen Type:
Recombinant Protein
Gene Name: SQSTM1 {ECO:0000303|PubMed:16286508, ECO:0000312|HGNC:HGNC:11280}
Gene ID: 8878
NCBI Accession: NP_001135770.1;NP_001135771.1;NP_003891.1
Primary Accession: Q13501
Other Accession: BC003139
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Other Names:
Sequestosome-1, EBI3-associated protein of 60 kDa, EBIAP, p60, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, SQSTM1, ORCA, OSIL
Antigen Type:
Recombinant Protein
Gene Name: SQSTM1 {ECO:0000303|PubMed:16286508, ECO:0000312|HGNC:HGNC:11280}
Gene ID: 8878
NCBI Accession: NP_001135770.1;NP_001135771.1;NP_003891.1
Primary Accession: Q13501
Other Accession: BC003139
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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