SRY Blocking Peptide (Center)

SRY Blocking Peptide (Center)

€363.00
In stock
SKU
AC-BP21539c
Catalog Number: AC-BP21539c
Size: 500 µg
Datasheet
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Background:
Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.

Other Names:
Sex-determining region Y protein, Testis-determining factor, SRY, TDF

Target/Specificity:
The synthetic peptide sequence is selected from aa 81-92 of HUMAN SRY

Gene Name: SRY {ECO:0000303|PubMed:1695712, ECO:0000312|HGNC:HGNC:11311}

Gene ID: 6736
Primary Accession: Q05066
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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