SSB (phospho-S366) polyclonal, anti-human
€328.00
In stock
SKU
BS4536
Background:
Ro/SSA is a ribonucleoprotein that binds to autoantibodies in 35 to 50% of patients with SLE and in up to 97% of patients with Sjogren syndrome. The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules. Most anti-Ro/SSA-positive sera have antibodies not only against the immunoreactive protein, but also against an Ro/SSA protein. The genes which encode the two proteins map to human chromosomes 11p15.5 and 1q31, respectively. La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and SLE.
Alternative Name:
Autoantigen La, La, La autoantigen, La autoantigen homolog, La protein, La ribonucleoprotein, La ribonucleoprotein domain family member 3, LA, LARP3, Lupus La antigen, Lupus La protein, Lupus La protein homolog, mRNA for autoantigen, Sjoegren syndrome type B antigen, Sjoegren syndrome type B antigen, Sjogren syndrome antigen B, SS B, SS-B, SS-B/La protein, SSB,
Application Dilution: WB: 1:500~1:1000
Specificity: p-SSB (S366) polyclonal antibody detects endogenous levels of SSB protein only when phosphorylated at Serine 366.
Immunogen:
Synthetic phosphopeptide derived from human SSB around the phosphorylation site of Serine 366.
MW: ~ 52 kDa
Swis Prot.: P05455
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 110% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Ro/SSA is a ribonucleoprotein that binds to autoantibodies in 35 to 50% of patients with SLE and in up to 97% of patients with Sjogren syndrome. The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules. Most anti-Ro/SSA-positive sera have antibodies not only against the immunoreactive protein, but also against an Ro/SSA protein. The genes which encode the two proteins map to human chromosomes 11p15.5 and 1q31, respectively. La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and SLE.
Alternative Name:
Autoantigen La, La, La autoantigen, La autoantigen homolog, La protein, La ribonucleoprotein, La ribonucleoprotein domain family member 3, LA, LARP3, Lupus La antigen, Lupus La protein, Lupus La protein homolog, mRNA for autoantigen, Sjoegren syndrome type B antigen, Sjoegren syndrome type B antigen, Sjogren syndrome antigen B, SS B, SS-B, SS-B/La protein, SSB,
Application Dilution: WB: 1:500~1:1000
Specificity: p-SSB (S366) polyclonal antibody detects endogenous levels of SSB protein only when phosphorylated at Serine 366.
Immunogen:
Synthetic phosphopeptide derived from human SSB around the phosphorylation site of Serine 366.
MW: ~ 52 kDa
Swis Prot.: P05455
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 110% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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