SSRP1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP14831b
Background:
The protein encoded by this gene is a subunit of aheterodimer that, along with SUPT16H, forms chromatintranscriptional elongation factor FACT. FACT interacts specificallywith histones H2A/H2B to effect nucleosome disassembly andtranscription elongation. FACT and cisplatin-damaged DNA may becrucial to the anticancer mechanism of cisplatin. This encodedprotein contains a high mobility group box which most likelyconstitutes the structure recognition element forcisplatin-modified DNA. This protein also functions as aco-activator of the transcriptional activator p63. An alternativelyspliced transcript variant of this gene has been described, but itsfull-length nature is not known.
Other Names:
FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80 kDa subunit, Facilitates chromatin transcription complex 80 kDa subunit, FACT 80 kDa subunit, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, hSSRP1, T160, SSRP1, FACT80
Gene Name: SSRP1
Gene ID: 6749
Primary Accession: Q08945
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a subunit of aheterodimer that, along with SUPT16H, forms chromatintranscriptional elongation factor FACT. FACT interacts specificallywith histones H2A/H2B to effect nucleosome disassembly andtranscription elongation. FACT and cisplatin-damaged DNA may becrucial to the anticancer mechanism of cisplatin. This encodedprotein contains a high mobility group box which most likelyconstitutes the structure recognition element forcisplatin-modified DNA. This protein also functions as aco-activator of the transcriptional activator p63. An alternativelyspliced transcript variant of this gene has been described, but itsfull-length nature is not known.
Other Names:
FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80 kDa subunit, Facilitates chromatin transcription complex 80 kDa subunit, FACT 80 kDa subunit, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, hSSRP1, T160, SSRP1, FACT80
Gene Name: SSRP1
Gene ID: 6749
Primary Accession: Q08945
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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