SSTR2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60470
Background:
SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.
Alternative Name:
Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1, SRIF 1, SRIF1, SSTR2
Application Dilution: WB: 1:500~1:1000
Specificity: SSTR2 polyclonal antibody detects endogenous levels of SSTR2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human SSTR2.
MW: ~ 80 kDa
Swis Prot.: P30874
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SSTRs (for somatostatin receptors) represent a family of G-protein-coupled receptors which mediate the diverse biological actions of somatostatin (SST). There are five distinct subtypes of SSTRs that bind two natural ligands, SST-14 and SST-28. SSTR2 gives rise to spliced variants, SSTR2A and 2B. SSTRs share common signaling pathways such as the ability to inhibit adenylyl cyclase via GTP binding proteins. Some of the subtypes are also coupled to tyrosine phosphatase (SSTR1,2), Ca2+ channels (SSTR2), Na+/H+ exchanger (SSTR1), PLA-2 (SSTR4), and MAP kinase (SSTR4). Individual target cells typically express more than one SSTR subtype and often all five isoforms. Subtypes of SSTR can form functional homo- and heterodimers.
Alternative Name:
Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1, SRIF 1, SRIF1, SSTR2
Application Dilution: WB: 1:500~1:1000
Specificity: SSTR2 polyclonal antibody detects endogenous levels of SSTR2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human SSTR2.
MW: ~ 80 kDa
Swis Prot.: P30874
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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