SSX4 antibody (clone 30000000000), anti-human
€435.00
In stock
SKU
AC-AT4049a
Catalog Number: AC-AT4049a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IF, E
Request Information AC-AT4049a">Request Information
Background:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Other Names:
Protein SSX4, Cancer/testis antigen 54, CT54, SSX4, SSX4A
Antigen Type:
Recombinant Protein
Gene Name: SSX4
Gene ID: 548313;6759
NCBI Accession: NP_001030004.1;NP_001035702.1;NP_005627.1;NP_783856.1
Primary Accession: O60224
Other Accession: NM_005636
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
Other Names:
Protein SSX4, Cancer/testis antigen 54, CT54, SSX4, SSX4A
Antigen Type:
Recombinant Protein
Gene Name: SSX4
Gene ID: 548313;6759
NCBI Accession: NP_001030004.1;NP_001035702.1;NP_005627.1;NP_783856.1
Primary Accession: O60224
Other Accession: NM_005636
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
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