ST14 antibody (clone 2F4), anti-human
€435.00
In stock
SKU
AC-AT4050a
Catalog Number: AC-AT4050a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
Request Information AC-AT4050a">Request Information
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E
Request Information AC-AT4050a">Request Information
Background:
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Other Names:
Suppressor of tumorigenicity 14 protein, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein, ST14, PRSS14, SNC19, TADG15
Antigen Type:
Recombinant Protein
Gene Name: ST14
Gene ID: 6768
NCBI Accession: NP_068813.1
Primary Accession: Q9Y5Y6
Other Accession: NM_021978
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Other Names:
Suppressor of tumorigenicity 14 protein, Matriptase, Membrane-type serine protease 1, MT-SP1, Prostamin, Serine protease 14, Serine protease TADG-15, Tumor-associated differentially-expressed gene 15 protein, ST14, PRSS14, SNC19, TADG15
Antigen Type:
Recombinant Protein
Gene Name: ST14
Gene ID: 6768
NCBI Accession: NP_068813.1
Primary Accession: Q9Y5Y6
Other Accession: NM_021978
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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