STAT1 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP19835b
Background:
The protein encoded by this gene is a member of the STATprotein family. In response to cytokines and growth factors, STATfamily members are phosphorylated by the receptor associatedkinases, and then form homo- or heterodimers that translocate tothe cell nucleus where they act as transcription activators. Thisprotein can be activated by various ligands includinginterferon-alpha, interferon-gamma, EGF, PDGF and IL6. This proteinmediates the expression of a variety of genes, which is thought tobe important for cell viability in response to different cellstimuli and pathogens. Two alternatively spliced transcriptvariants encoding distinct isoforms have been described. [providedby RefSeq].
Other Names:
Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1
Target/Specificity:
The synthetic peptide sequence is selected from aa 732-745 of HUMAN STAT1
Gene Name: STAT1
Gene ID: 6772
Primary Accession: P42224
Other Accession: NP_009330.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of the STATprotein family. In response to cytokines and growth factors, STATfamily members are phosphorylated by the receptor associatedkinases, and then form homo- or heterodimers that translocate tothe cell nucleus where they act as transcription activators. Thisprotein can be activated by various ligands includinginterferon-alpha, interferon-gamma, EGF, PDGF and IL6. This proteinmediates the expression of a variety of genes, which is thought tobe important for cell viability in response to different cellstimuli and pathogens. Two alternatively spliced transcriptvariants encoding distinct isoforms have been described. [providedby RefSeq].
Other Names:
Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84, STAT1
Target/Specificity:
The synthetic peptide sequence is selected from aa 732-745 of HUMAN STAT1
Gene Name: STAT1
Gene ID: 6772
Primary Accession: P42224
Other Accession: NP_009330.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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