STAT1 (clone 6C2-F7-D12), anti-human, monkey

Background:
The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein can be activated by various ligands including interferon-alpha,interferon-gamma,EGF,PDGF and IL6.This protein mediates the expression of a variety of genes,which is thought to be important for cell viability in response to different cell stimuli and pathogens.Two alternatively spliced transcript variants encoding distinct isoforms have been described.[provided by RefSeq,Jul 2008]

Synonyms: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91

Cellular Location: Cytoplasm Nucleus

Immunogen:
Purified recombinant human STAT1 protein fragments expressed in E.coli

Gene Symbol: STAT1

Gene ID: 6772

Swiss prot: P42224

Calculated MW: 91kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.