STAT2 antibody (clone 5G7), anti-human
€435.00
In stock
SKU
AC-AT4061a
Catalog Number: AC-AT4061a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IF, E
Request Information AC-AT4061a">Request Information
Background:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Signal transducer and activator of transcription 2, p113, STAT2
Antigen Type:
Recombinant Protein
Gene Name: STAT2
Gene ID: 6773
NCBI Accession: NP_005410.1;NP_938146.1
Primary Accession: P52630
Other Accession: BC051284
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Signal transducer and activator of transcription 2, p113, STAT2
Antigen Type:
Recombinant Protein
Gene Name: STAT2
Gene ID: 6773
NCBI Accession: NP_005410.1;NP_938146.1
Primary Accession: P52630
Other Accession: BC051284
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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